Vaccine Response Assays

  • Immunization and infectious challenge (See in vivo preclinical models)
  • Protection assay
  • NA assay
  • Humoral response characterization:
    – microneutralization (MN)
    – hemagglutination inhibition assays (HAI)
  • Viral titration (nasal wash, oropharyngeal/nasopharyngeal/rectal swabs,
    feces, lung and other organs)
  • Cytokine evaluation (Luminex)
  • Antibody quantification by Enzyme-linked immunosorbent assay (ELISA) and Enzyme-linked immunospot (ELISpot)